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Mode of Action of Chemical Agents

Chemical agents act on microorganisms by:

  • They may damage the lipids and proteins of the cytoplasmic membrane of microorganisms.
  • They may denature microbial enzymes and other proteins usually by disrupting the hydrogen and disulfide bonds that give the protein its 3-D shape. This blocks metabolism function.

Modes Of Action

Mechanisms Of Resistance:-

  • Most antimicrobials fall into one of four main categories, based on their site of activity.
  • These include inhibition of cell wall synthesis, protein synthesis, nucleic acid synthesis, or disruption of cell membrane integrity.

There are a number of factors which influence the antimicrobial action of disinfectants and antiseptics, including:-

  • The concentration of the chemical agent.
  • The temperature at which the agent is being used.
  • The number of microorganisms present.
  • The nature of the material bearing the microorganisms.
  • The chemical agent that kills bacteria is Bactericide.