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Updated National Immunization Schedule Chart

Immunization/vaccination produce a response in the body that is similar to the body’s response to a natural infection (Table 11.4). Immunization or vaccines can therefore protect the body from a disease before the disease has a chance to cause illness. Immunization has helped to reduce the impact of communicable disease on health and well being.

Some diseases have been well controlled and other has been eliminated from some parts of the world because of vaccination. Stopping vaccination may lead to epidemic.

Table 11.4: National immunization schedule


Due age


BCG At birth Intra dermal
Hepatitis B-Birth dose At birth Intra muscular
OPV-O At birth Oral
OPV 1, 2 & 3 At 6 weeks, 10 weeks & 14 weeks Oral
Pentavalent 1, 2 & 3 (Diphtheria + Pertuss is +
Tetanus + Hepatitis B + Hib)
At 6 weeks, 10 weeks & 14 weeks Intra muscular
Inactivated polio vaccine At 6 & 14 weeks Intra muscular
Rotavirus (where applicable) At 6 weeks, 10 weeks & 14 weeks Oral
Pneumococcal conjugate
vaccine (where applicable)
At 6 weeks & 14 weeks. At 9 completed months -booster Intra muscular
Measles/Rubella 1st dose At 9 completed months – 12 months Subcutaneous
DPT Booster-1 16–24 months Intra muscular
Measles/Rubella 2nd dose  16–29 months Subcutaneous
OPV Booster 16–24 months Oral
DPT Booster – 2 5–6 years Intra muscular
TT 10 years & 16 years Intra muscular

proteins, antibodies and hormones. There are four kinds of ELISA assay tests. They are: Direct ELISA, Indirect ELISA, Sandwich ELISA and Competitive ELISA. Western blotting technique is used for the identification of particular protein from the mixture of proteins.

The most common protein sample used for Western blotting is cell lysate. Blotting refers to the transfer of the protein from the gel to the nitrocellulose paper by capillary action.

The substances causing allergic/hypersensitivity is known as allergens. Allergic rhinitis develops when the body’s immune system becomes sensitized and overreacts to something in the environment like pollen grains, strong odour of perfumes, dust etc.

Certain drugs such as penicillin, cephalosporin and streptomycin can absorb non-specifically to protein on surface of RBC forming complex similar to hapten-carrier complex.

Transfer of living cells, tissues or organs from one part of the body to another or from one individual to another is known as transplantation. The graft tissue antigens induce an immune response in the host. This type of immune response is called host versus graft reaction. The ultimate goal of any immunization program is the eradication of the disease.

Active natural immunization involves activation of immune system in the body to produce antibodies. It is achieved in both clinical and subclinical infections Immunization has helped to reduce the impact of communicable disease on health and well being.